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Collectively, these in vivo data demonstrate that dual-pathway inhibition synergistically overcomes MAGI3 deficiency-driven tumor growth and resistance, providing a compelling rationale for co-targeting mTOR and Wnt/-catenin in this aggressive ccRCC subtype

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In addition to Ashi points (around skin lesions, 0.51 cm away from the rash), Jiaji (Ex-B 2) points on the affected side can be selected [30]

J Biol Chem 1997;272:17269-75

Interestingly, a recent study proposed novel early secretory phase-specific markers showing that epithelial cell differentiation is not yet completed during this phase, with luminal and glandular cells remaining in a pre-luminal and pre-glandular state, respectively [25]

Cell Genomics 4 , 100638 (2024)